10 Warning Signs of APDS
If you or someone you know is affected by two or more of the warning signs, speak to a physician about the possibility of APDS.
The 10 Warning Signs of APDS were developed in partnership with Pharming.
- Two or more of the following in one year:Sinus Infections, Pneumonias, Ear Infections
- Developmental delays including cognitive delays and/or growth delays(i.e., short stature)
- Persistent lymph node swelling
- Frequent and severe diarrhea lasting more than four weeks
- Enlarged liver and/or spleen
- Diagnosed autoimmune or autoinflammatory conditions(especially if early age of onset or multiple autoimmune conditions)
- Recurrent and difficult to treat herpes viral infections(especially if CMV/EBV are chronic)
- Persistent cough, uncontrolled or difficult to control asthma or scarring of lungs for no clear reason(known as bronchiectasis)
- Lymphoma or family history of lymphoma(a group of cancers affecting the lymph nodes)
- Family history of another primary immunodeficiency disease or CVID
If you or someone you know is experiencing any symptoms of Primary Immunodeficiency, the 4 Stages of Testing provides a structured diagnostic pathway. This evidence-based framework helps physicians accurately diagnose PI and has been translated into dozens of languages to enhance early diagnosis worldwide.
